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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8944 | TTA-A2 | Calcium Channel | |
TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels ... | |||
T64203 | T-Type calcium channel inhibitor 2 | ||
T-Type calcium channel inhibitor 2 (compound 6g) is a potent inhibitor of the T-type calcium channel, acting on Cav3.1 (α1G) (IC50: 31.0 μM), Cav3.2 (α1H) (IC50: 83.1 μM), Cav3.3 (α1I) (α1H) ( T-Type calcium channel inhi... | |||
T0283 | Trimethadione | 3,5,5,-Trimethyloxazolidine-2,4-dione | Calcium Channel |
Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) is a dione-type anticonvulsant with antiepileptic activity. | |||
T71990 | TTA-A8 | Calcium Channel | |
TTA-A8 is an antagonist of T-type calcium channel. | |||
T3703 | ABT-639 | ABT 639 | Calcium Channel |
ABT-639 is a potent and selective T-type calcium channel blocker. | |||
T2323 | Efonidipine | (±)-Efonidipine,NZ-105 | Calcium Channel |
Efonidipine (NZ-105)(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels. | |||
T12032 | Mibefradil dihydrochloride | Ro 40-5967 (dihydrochloride) | Calcium Channel |
Mibefradil dihydrochloride (Ro 40-5967 (dihydrochloride)) is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-type currents with IC50s of 2.7 μM and 18.6 μM, respectively). | |||
T12238 | NNC 55-0396 | NNC 55-0396 dihydrochloride | Calcium Channel |
NNC 55-0396 is a highly selective blocker of T-type calcium channel with IC50 of 6.8 μM. NNC 55-0396 can be used in studies about preventing human ovarian cancer cell proliferation. | |||
T29201 | Z944 | Z 944,Z-944 | Calcium Channel |
Z944 is a T-type calcium channel blocker. Z944 delays the progression of seizures in the amygdala kindling model. Z944 disrupts prepulse inhibition in both epileptic and non-epileptic rats. | |||
T8448 | ZSET1446 | ZSET-1446,ST-101 | Calcium Channel , AChR |
ZSET1446 (ST-101) is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models. | |||
T0728 | Ethosuximide | Zarontin | Calcium Channel |
Ethosuximide (Zarontin) is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other types of seizures. | |||
T13219 | TTA-Q6 | Calcium Channel | |
TTA-Q6 is a selective T-type Ca2+ channel antagonist with potential antitumor and immunomodulatory activity for the treatment of neurological disorders by inhibiting the uptake of extracellular calcium ions by tumor cell... | |||
T64387 | 2-Nitrobenzoic acid | o-Nitrobenzoic acid | Others |
2-Nitrobenzoic acid (o-Nitrobenzoic acid) is a antiproliferation agent. 2-Nitrobenzoic acid shows IC50 of 8.3 μM to jurkat cell line expressing T type calcium channel alpha 1H or its splice variant delta 25. | |||
T0267 | Zonisamide | AD 810,CI 912 | Calcium Channel , Sodium Channel , Carbonic Anhydrase |
Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms... | |||
T71202 | A-1048400 | ||
A-1048400 is a potent and selective N-type and T-type calcium channel blocker. | |||
TQ0153 | Mibefradil | Ro 40-5967 | Calcium Channel |
Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents). | |||
T69809 | NNL-2 | ||
NNL-2 is a synthetic cannabinoid and T-type calcium channel inhibitor. This product is for research use only. | |||
T62402 | TTA-P2 | ||
TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of the T-type calcium channel. TTA-P2 effectively penetrates the CNS and blocks natural T-type currents in deep cerebellar nucleus neurons, completely elimi... | |||
T14120 | ACT-709478 | Others | |
ACT-709478 is a potent, selective T-type calcium channel blocker that is orally active and capable of penetrating the brain. It is currently utilized in research focusing on generalized epilepsies[1]. | |||
T60648 | IAB15 | ||
IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1]. |