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Search Results for " t-type calcium channel "

20

Compounds

Cat No. Product Name Synonyms Targets
T8944 TTA-A2 Calcium Channel
TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels ...
T64203 T-Type calcium channel inhibitor 2
T-Type calcium channel inhibitor 2 (compound 6g) is a potent inhibitor of the T-type calcium channel, acting on Cav3.1 (α1G) (IC50: 31.0 μM), Cav3.2 (α1H) (IC50: 83.1 μM), Cav3.3 (α1I) (α1H) ( T-Type calcium channel inhi...
T0283 Trimethadione 3,5,5,-Trimethyloxazolidine-2,4-dione Calcium Channel
Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) is a dione-type anticonvulsant with antiepileptic activity.
T71990 TTA-A8 Calcium Channel
TTA-A8 is an antagonist of T-type calcium channel.
T3703 ABT-639 ABT 639 Calcium Channel
ABT-639 is a potent and selective T-type calcium channel blocker.
T2323 Efonidipine (±)-Efonidipine,NZ-105 Calcium Channel
Efonidipine (NZ-105)(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.
T12032 Mibefradil dihydrochloride Ro 40-5967 (dihydrochloride) Calcium Channel
Mibefradil dihydrochloride (Ro 40-5967 (dihydrochloride)) is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-type currents with IC50s of 2.7 μM and 18.6 μM, respectively).
T12238 NNC 55-0396 NNC 55-0396 dihydrochloride Calcium Channel
NNC 55-0396 is a highly selective blocker of T-type calcium channel with IC50 of 6.8 μM. NNC 55-0396 can be used in studies about preventing human ovarian cancer cell proliferation.
T29201 Z944 Z 944,Z-944 Calcium Channel
Z944 is a T-type calcium channel blocker. Z944 delays the progression of seizures in the amygdala kindling model. Z944 disrupts prepulse inhibition in both epileptic and non-epileptic rats.
T8448 ZSET1446 ZSET-1446,ST-101 Calcium Channel , AChR
ZSET1446 (ST-101) is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models.
T0728 Ethosuximide Zarontin Calcium Channel
Ethosuximide (Zarontin) is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other types of seizures.
T13219 TTA-Q6 Calcium Channel
TTA-Q6 is a selective T-type Ca2+ channel antagonist with potential antitumor and immunomodulatory activity for the treatment of neurological disorders by inhibiting the uptake of extracellular calcium ions by tumor cell...
T64387 2-Nitrobenzoic acid o-Nitrobenzoic acid Others
2-Nitrobenzoic acid (o-Nitrobenzoic acid) is a antiproliferation agent. 2-Nitrobenzoic acid shows IC50 of 8.3 μM to jurkat cell line expressing T type calcium channel alpha 1H or its splice variant delta 25.
T0267 Zonisamide AD 810,CI 912 Calcium Channel , Sodium Channel , Carbonic Anhydrase
Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms...
T71202 A-1048400
A-1048400 is a potent and selective N-type and T-type calcium channel blocker.
TQ0153 Mibefradil Ro 40-5967 Calcium Channel
Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).
T69809 NNL-2
NNL-2 is a synthetic cannabinoid and T-type calcium channel inhibitor. This product is for research use only.
T62402 TTA-P2
TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of the T-type calcium channel. TTA-P2 effectively penetrates the CNS and blocks natural T-type currents in deep cerebellar nucleus neurons, completely elimi...
T14120 ACT-709478 Others
ACT-709478 is a potent, selective T-type calcium channel blocker that is orally active and capable of penetrating the brain. It is currently utilized in research focusing on generalized epilepsies[1].
T60648 IAB15
IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].
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TargetMol